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Index of Cleared Science Reviews

Lindane (Pc Code 009001)


July 21, 1981. Memorandum. 6 Page(s).
Janice Jensen. Environmental Fate Branch.
Lindane Dietary Exposure Analysis - PD 4.

August 1, 1982. Report. 82 Page(s).
Committee on Toxicology. National Research Council.
An Assessment of the Health Risks of Seven Pesticides Used 
for Termite Control.

June 17, 1983. Memorandum. 32 Page(s).
Krystyna Locke. Toxicology Branch.
Lindane: Subchronic Oral Dosing (Rat) Study and a 
Metabolic Study (Mouse). 
Acc. 250340-250342, 250339.

July 22, 1983. Memorandum. 2 Page(s).
John Chen. Toxicology Branch.
Lindane 20954-Q: Review of Protocol for the In Vivo Sister 
Chromatid Exchange Assay in CFI-Mouse Bone Marrow Cells 
(RCC Draft Protocol, Itingen/Schweiz). Caswell #527.

December 27, 1983. Memorandum. 8 Page(s).
Herman Gibb. Carcinogen Assessment Group.
Review of the Gilbert et al. Study of Wood Treaters in 
Hawaii.
Attachment(s) following:

     September 16, 1983. Memorandum. Page(s).
     Charles Ris. Carcinogen Assessment Group.
     1981 Hawaii Epidemiology Study Submitted to the Office of 
     Solid Waste by Reichhold and Vulcan Companies for Section 
     3001 Dioxin Docket.

     September 16, 1983. Memorandum. Page(s).
     David Bayliss. Carcinogen Assessment Group.
     1981 Hawaii Epidemiology Study, July 1983 (Effects of 
     Chemical Preservatives on the Health of Wood Treating 
     Workers in Hawaii, 1981).

September 25, 1984. Memorandum. 7 Page(s).
Irving Mauer. Toxicology Branch.
Lindane: Review of Mutagenicity Data in Response 
to Lindane PD-4 and 3(c)(2)(B) Letter of June 6, 1984. 
Accession #253997/EPA Reg. Nos. 359-686, 359-687, 21137-3 
and 40083-1. 
Pages 4-7 removed, registrant data.

September 27, 1984. Memorandum. 8 Page(s).
Irving Mauer. Toxicology Branch.
Lindane - Mutagenicity Data in Response to PD-4 on Lindane. 
Accession #254504/EPA Reg. Nos. 359-686, 359-687, 40083-1 
and 21137-3. Caswell No. 527. 
Pages 5-8 removed, registrant data.

November 9, 1984. Review. 2 Page(s).
Frank Davido. Exposure Assessment Branch.
Lindane. Review Indoor Air Monitoring Study.

May 12, 1985. Data Eval. Recs. 30 Page(s).
Ann Stavola. Ecological Effects Branch.
Package of data evaluation records concerning the toxicity 
of lindane.

May 16, 1985. Final Report. 67 Page(s).
Dynamac Corporation. Environmental Fate & Ground Water Branch.
Task 1: Review and Evaluation of Individual Studies.

May 30, 1985. Memorandum. 15 Page(s).
Hudson Boyd. Exposure Assessment Branch.
Data for Registration Standard - Lindane.

June 3, 1985. Memorandum. 7 Page(s).
Richard M. Lee. Ecological Effects Branch.
Lindane Registration Standard (Beneficial Insects Portion).

June 6, 1985. Data Eval. Rec. 1 Page(s).
Ann Stavola. Ecological Effects Branch.
Toxicity of pesticides to wildlife.

June 6, 1985. Data Eval. Rec. 2 Page(s).
Ann Stavola. Ecological Effects Branch.
The Acute Oral Toxicity of 369 Pesticidal, Pharmaceutical 
and Other Chemicals to Wild Birds.

June 6, 1985. Data Eval. Rec. 2 Page(s).
Ann Stavola. Ecological Effects Branch.
Lethal Dietary Toxicities of Environmental Pollutants to 
Birds: Special Scientific Report.

June 6, 1985. Data Eval. Rec. 14 Page(s).
Ann Stavola. Ecological Effects Branch.
Residues in Fish, Wildlife, and Estuaries.

June 6, 1985. Data Eval. Rec. 7 Page(s).
Ann Stavola. Ecological Effects Branch.
Toxicity of Seed-dressing Products for Partridge 
and Pheasant.

June 6, 1985. Data Eval. Rec. 4 Page(s).
Ann Stavola. Ecological Effects Branch.
The Effects on Birds of Certain Chlorinated Insecticides 
Used as Seed Dressings.

June 6, 1985. Data Eval. Rec. 8 Page(s).
Ann Stavola. Ecological Effects Branch.
Relative Toxicity of Ten Chlorinated Hydrocarbon 
Insecticides to Four Species of Fish.

June 6, 1985. Data Eval. Rec. 2 Page(s).
Ann Stavola. Ecological Effects Branch.
Handbook of Acute Toxicity of Chemicals to Fish and 
Aquatic Invertebrates.

June 6, 1985. Data Eval. Rec. 7 Page(s).
Ann Stavola. Ecological Effects Branch.
Acute Toxicity of Some Organic Insecticides to Three 
Species of Salmonids and to the Threespine Stickleback.

June 6, 1985. Data Eval. Rec. 2 Page(s).
Ann Stavola. Ecological Effects Branch.
Toxicity of Pesticides to the Crustacean 
"Gammarus iacustris".

June 6, 1985. Data Eval. Rec. 13 Page(s).
Ann Stavola. Ecological Effects Branch.
Toxicity of Some Insecticides to Four Species of 
Malacostracan Crustaceans.

June 6, 1985. Data Eval. Rec. 6 Page(s).
Ann Stavola. Ecological Effects Branch.
Pesticide Toxicities to Tadpoles of the Western Chorus 
Frog "Pseudacris triseriata" and Fowler's Toad 
"Bufo woodhousii fowleri".

June 6, 1985. Data Eval. Rec. 7 Page(s).
Ann Stavola. Ecological Effects Branch.
Acute Toxicities of Insecticides to Marine 
Decapod Crustaceans.

June 6, 1985. Data Eval. Rec. 2 Page(s).
Ann Stavola. Ecological Effects Branch.
Excerpt from the Handbook of Acute Toxicity of Chemicals 
to Fish and Aquatic Invertebrates.

June 12, 1985. Memorandum. 21 Page(s).
Ann Stavola. Ecological Effects Branch.
Lindane Registration Standard.

July 11, 1985. Science Chapter. 14 Page(s).
John Doherty. Toxicology Branch.
Submission of the Toxicology Branch Chapter of the 
Registration Standard for Lindane. Tox Chem. No. 527.

July 25, 1985. Memorandum. 6 Page(s).
Ann Stavola. Ecological Effects Branch.
Addendum to the Ecological Effects Branch's Chapter 
and Data Table for the Lindane Standard.

August 13, 1985. Memorandum. 2 Page(s).
Allan Reiter. Residue Chemistry Branch.
EPA Reg. No. 239-2363. Amended Use, Lindane on Tomatoes 
(No Accession Number. RCB No. 1163).

August 14, 1985. Memorandum. 1 Page(s).
John Doherty. Toxicology Branch.
Lindane Registration Standard: Addendum - Requirement for 
Additional Metabolism Data.

August 26, 1985. Memorandum. 7 Page(s).
John Doherty. Toxicology Branch.
Lindane Registration Standard - Addendum to the Toxicology 
Branch Chapter - Review of Metabolism in Mammals Data. 
Tox Review 004629.

February 12, 1986. Memorandum. 5 Page(s).
John Doherty. Toxicology Branch.
Lindane - Special Review - Response to the Letter from 
Mr. C.A. O'Connor and Ms. M.K. Tandy Dated October 22, 1985;
Reply to Comments Made by Dr. M. Herbst Related to 
Interpretation of the Rat Kidney Pathology; Review of 
Selected Papers Related to the Health Status of Workers...

March 10, 1986. Review. 7 Page(s).
Joseph C. Reinert. Exposure Assessment Branch.
Rebuttal to Exposure Assessment.

March 24, 1986. Memorandum. 7 Page(s).
Cynthia Deyrup. Residue Chemistry Branch.
Lindane Dermal Application Metabolism Study Protocol. 
RCB #514. No RD Accession Number.

April 2, 1986. Review. 2 Page(s).
Joseph C. Reinert. Exposure Assessment Branch.
Exposure Study Protocol.

April 25, 1986. Memorandum. 5 Page(s).
Richard Felthousen. Ecological Effects Branch.
CIEL/Lindane Registration Standard - Protocol Review.

April 25, 1986. Memorandum. 15 Page(s).
John Doherty. Toxicology Branch.
Lindane - Special Review: Review of a Rat Subchronic 
Inhalation Toxicity Study with Lindane. 
Tox review 005059.

June 13, 1986. Review. 6 Page(s).
Richard Felthousen, et. al. Ecological Effects Branch.
Registrant Request for Waiver of 7-Day Feeding Study 
with Bobwhite Quail and Red-winged Blackbirds.

June 24, 1986. Memorandum. 7 Page(s).
John Doherty. Toxicology Branch.
EPA ID No. 009001: Lindane: Toxicology Branch 
Position On Potential Toxicity Via Inhalation to the 
Kidneys and Blood (Bone Marrow) as Noted in the 
Subchronic (90 day) Inhalation Study Translated 
from German.

July 15, 1986. Review. 4 Page(s).
Emil Regelman. Exposure Assessment Branch.
Reg. No. 359-710. Lindane HGI. Review of Proposed Protocol.

July 22, 1986. Memorandum. 6 Page(s).
John Doherty. Toxicology Branch.
Lindane: Company Meeting to Discuss Protocols for the Rat 
Chronic Feeding/Oncogenicity Study.

August 18, 1986. Memorandum. 6 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 359-686 - Lindane: Review of Protocols for 
90-Day Dermal Toxicity Studies in Rats and Rabbits and 
14-Week Aerosol Inhalation Study in Mice.

September 16, 1986. Review. 3 Page(s).
Ann Stavola. Ecological Effects Branch.
Submission of Revised Protocol for Aquatic Residue Testing.

November 18, 1986. Review. 4 Page(s).
Herbert L. Manning. Exposure Assessment Branch.
164-1 Terrestrial Field Dissipation Protocol.

December 2, 1986. Review. 8 Page(s).
Ann Stavola. Ecological Effects Branch.
Data from Several Acute Toxicity Tests.

December 5, 1986. Memorandum. 4 Page(s).
John Doherty. Toxicology Branch.
Lindane: Notes Related to a Company Meeting to Discuss the 
Revised Protocol for the Rat Chronic Feeding/Oncogenicity 
Study.

December 24, 1986. Memorandum. 27 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 359-686. Lindane: Review of Protocol for the 
Rat Chronic Feeding and Oncogenicity Study (Life Science 
Research, Prepared October, 1986). 
Pages 6-27 are not included - registrant data.

December 30, 1986. Review. 6 Page(s).
Allen W. Vaughn, et. al. Ecological Effects Branch.
Submission of Honey Bee Toxicity Data to Support 
Registration Standard.

December 31, 1986. Data Eval. Rec. 5 Page(s).
Ann Stavola. Ecological Effects Branch.
Invertebrate Acute Toxicity Test. Daphnia Magna.

December 31, 1986. Data Eval. Rec. 5 Page(s).
Ann Stavola. Ecological Effects Branch.
Invertebrate Acute Toxicity Test. Daphnia Magna.

December 31, 1986. Data Eval. Rec. 5 Page(s).
Ann Stavola. Ecological Effects Branch.
Invertebrate Acute Toxicity Test. Daphnia Magna.

December 31, 1986. Data Eval. Rec. 4 Page(s).
Ann Stavola. Ecological Effects Branch.
Avian Acute Oral Study. Bobwhite Quail 
(Colinus virginianus).

December 31, 1986. Data Eval. Rec. 5 Page(s).
Ann Stavola. Ecological Effects Branch.
Fish Static Acute Toxicity Test. Rainbow Trout 
(Salmo gairdneri).

December 31, 1986. Data Eval. Rec. 5 Page(s).
Ann Stavola. Ecological Effects Branch.
Fish Static Acute Toxicity Test. 
Bluegill (Lepomis macrochirus).

December 31, 1986. Data Eval. Rec. 5 Page(s).
Ann Stavola. Ecological Effects Branch.
Fish Static Acute Toxicity Test. 
Bluegill Sunfish (Lepomis macrochirus).

December 31, 1986. Data Eval. Rec. 5 Page(s).
Ann Stavola. Ecological Effects Branch.
Fish Static Acute Toxicity Test. 
Bluegill - Lepomis macrochirus.

December 31, 1986. Data Eval. Rec. 5 Page(s).
Ann Stavola. Ecological Effects Branch.
Fish Static Acute Toxicity Test. 
(Salmo gairdneri).

December 31, 1986. Data Eval. Rec. 5 Page(s).
Ann Stavola. Ecological Effects Branch.
Fish Static Acute Toxicity Test. 
Rainbow Trout (Salmo gairdneri).

December 31, 1986. Data Eval. Rec. 6 Page(s).
Ann Stavola. Ecological Effects Branch.
Oyster Embryolarvae Acute Toxicity. 
(Crassostrea virginica).

January 16, 1987. Memorandum. 20 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 359-686. Lindane: Review of Protocol for a 
13-Week Dermal Toxicity Study with Rats. 
Pages 5-20 are not included - registrant data.

January 16, 1987. Memorandum. 20 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 359-686. Lindane: Review of Protocol for a 
13-Week Dermal Toxicity Study with Rabbits. 
Pages 5-20 are not included - registrant data.

January 16, 1987. Memorandum. 10 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 359-686. Lindane: Review of a Protocol for a 
5-Day Pilot Inhalation Study with Mice. 
Pages 4-10 removed, registrant data.

January 27, 1987. Memorandum. 16 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 359-686. Lindane: Review of the Protocol for 
a 14-Week Inhalation Study with Mice (Bushy Run Research 
Center, Project No. 86-85-80201). 
Pages 5-16 removed, registrant data.

February 2, 1987. Memorandum. 10 Page(s).
John Doherty. Toxicology Branch.
EPA Data Submitter No. 52904-C. Lindane: Review of Acute 
Inhalation LC50, Primary Eye Irritation, Primary Dermal 
Irritation, and Dermal Sensitization Studies. 
Tox Review 005703.

February 24, 1987. Memorandum. 2 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 359-686. Lindane: Amendment to the Protocol 
for the Rat Chronic Feeding/Oncogenicity Study Concerning 
the 30-Day Sampling Time for Blood, Urine and Clinical 
Chemistries (Life Science Research Protocol Prepared 
October, 1986).

April 13, 1987. Memorandum. 3 Page(s).
Edwin Budd. Toxicology Branch.
Lindane Special Review - Reassessment of Toxicological 
Significance of Kidney Lesions Observed in Rat Studies.
Attachment(s) following:

     January 8, 1987. Memorandum. 4 Page(s).
     David Jaquith. Exposure Assessment Branch.
     Exposure of Workers to Lindane During Forestry and Hardwood 
     Lumber Use.

     June 24, 1986. Memorandum. 7 Page(s).
     John Doherty. Toxicology Branch.
     EPA ID No. 009001: Lindane: Toxicology Branch Position on 
     Potential Toxicity Via Inhalation to the Kidneys and Blood 
     (Bone Marrow) as Noted in the Subchronic (90-Day) Inhalation
     Study Translated from German. Record No. 174083.

     September 18, 1985. Memorandum. 4 Page(s).
     Kyle Barbehenn. Science Integration Staff.
     Further Revision of Lindane Risks.

     August 14, 1986. Memorandum. 3 Page(s).
     John Doherty. Toxicology Branch.
     Theoretical Margins of Safety for Lindane Exposure: 
     Recalculation to Include Both Dermal and Inhalation Exposure
     for Specified Uses.

     September 11, 1986. Briefing. 8 Page(s).
     Carol Monroe. Special Review Branch.
     Briefing on Lindane.

April 17, 1987. Memorandum. 21 Page(s).
John Doherty. Toxicology Branch.
Lindane: Toxicology Branch Comments on the Revised 
(March, 1987) Protocols for Rat and Rabbit 90-Day Dermal 
Toxicity Studies. 
Pages 3-21 removed, registrant data.

April 17, 1987. Memorandum. 3 Page(s).
John Doherty. Toxicology Branch.
Lindane: Toxicology Branch comments on the revised (March, 
1987) protocols for rat and rabbit 90 day dermal toxicity 
studies.

April 21, 1987. Memorandum. 9 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 359-686. Lindane: Review of Registrants 
Comments on the Protocols for the 5-Day Pilot Inhalation 
Study and 14-Week Inhalation Study with Lindane.

April 21, 1987. Memorandum. 27 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 359-686. Lindane: Review of Revised Protocol 
for the Rat Chronic Feeding/Oncogenicity Study. 
Pages 3-27 removed, registrant data.

April 28, 1987. Memorandum. 2 Page(s).
Maxie Jo Nelson. Residue Chemistry Branch.
EPA Reg. No. 359-686. Lindane. Request for Time Extension.
RCB #2184. MRID # None.

May 12, 1987. Review. 10 Page(s).
David Jaquith. Exposure Assessment Branch.
Applicator Exposure Study Review.

May 27, 1987. Memorandum. 9 Page(s).
Robert Zendzian. Toxicology Branch.
Lindane, Dermal Absorption Studies in Rat and Rabbit. 
Tox Review 005914.

June 24, 1987. Memorandum. 2 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 359-686 - Lindane. Supplementary Information 
Related to the Use of Multistix Reagent Strips and Clinitest
Reagent Tablets to be Used for Urine Analysis in the Chronic
Feeding Oncogenicity Study.

July 8, 1987. Data Eval. Rec. 4 Page(s).
P. Mastradone. Exposure Assessment Branch.
Degradation - Photodegradation on Soil 
Acc. 265725.

July 8, 1987. Data Eval. Rec. 8 Page(s).
P. Mastradone. Exposure Assessment Branch.
Mobility - Laboratory Volatility 
Acc. 265721.

July 14, 1987. Review. 33 Page(s).
Emil Regelman. Exposure Assessment Branch.
Flagged Data in Response to Registration Standard.

August 20, 1987. Review. 2 Page(s).
Michael Firestone. Exposure Assessment Branch.
Review of Benefits/Use Document.

August 28, 1987. Memorandum. 3 Page(s).
David Jaquith. Exposure Assessment Branch.
Exposure Assessment for Lindane Use on Bedbugs and for 
Control of Clothes Moths.

September 2, 1987. Memorandum. 5 Page(s).
Robert Zendzian. Toxicology Branch.
Lindane, MOS's for Selected Use Patterns.

September 18, 1987. Review. 5 Page(s).
Michael Firestone. Exposure Assessment Branch.
Human Exposure Assessment.

November 6, 1987. Review. 8 Page(s).
Emil Regelman. Exposure Assessment Branch.
Review of Laboratory Volatility Studies.

December 17, 1987. Memorandum. 3 Page(s).
John Doherty. Toxicology Branch.
Lindane: Toxicology Branch Response to the Letter from 
Mr. Matthew J. McGrath Concerning 1) Extension of the Due 
Date for the Mouse Inhalation Study, 2) Evaluation of Bone 
Marrow Myelograms in the Mouse Inhalation Study, 3) 
Progress of the Subchronic Dermal Studies in Rats..

February 25, 1988. Memorandum. 1 Page(s).
Cynthia Deyrup. Residue Chemistry Branch.
Partial Response (11/10/87) by Centre International d'Etudes
du Lindane (CIEL) to Data Gaps Cited in the Residue 
Chemistry Chapter of the 9/30/85 Lindane Registration 
Standard. (RCB #3256). MRID No. 404312-09.

March 1, 1988. Memorandum. 14 Page(s).
Laurie Lewis. Exposure Assessment Branch.
Exposure Assessment for Lindane Greenhouse Uses.

March 3, 1988. Memorandum. 2 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 359-686 - Lindane: Registrant's Request to 
Revise the Protocol for Rabbit 90-Day Dermal Toxicity Study.
Problems Involved in Conducting a 90-Day Dermal Toxicity at 
the Hazleton (UK) Laboratories.

March 9, 1988. Review. 5 Page(s).
Paul Mastradone. Exposure Assessment Branch.
Review Fish Bioaccumulation Study.

March 21, 1988. Review. 21 Page(s).
Michael Firestone. Exposure Assessment Branch.
Applicator Exposure Study.

March 24, 1988. Memorandum. 23 Page(s).
Gary Otakie. Residue Chemistry Branch.
Partial Response (November 10, 1987) by Centre International
d'Etudes du Lindane (CIEL) to Data Gap S171-4 (Nature of the
Residue in Plants as Identified in the Residue Chemistry 
Chapter of the September 30, 1985 Lindane Registration 
Standard... MRID 404312-01, 404312-04, 404109-02.

March 24, 1988. Memorandum. 2 Page(s).
John Onley. Residue Chemistry Branch.
Partial Response (Cover Letter of 12/1/87) by the Law Firm 
of McKenna, Conner, & Cuneo on Behalf of Centre 
International d'Etudes du Lindane (CIEL) Pertinent to Data 
Gap S171-4 as Identified in the Residue Chemistry Chapter of
the 9/30/85 Lindane Registration Standard.

March 24, 1988. Memorandum. 17 Page(s).
Cynthia Deyrup. Residue Chemistry Branch.
Partial Response (7/21/87) by Centre International d'Etudes 
du Lindane (CIEL) to Data Gap S171-4 (Nature of the Residue 
in Livestock Ruminants) as Identified in the Residue 
Chemistry Chapter of the 9/30/85 Lindane Registration 
Standard. (RCB #3312). MRID No. 402713-02.

March 24, 1988. Memorandum. 12 Page(s).
John Onley. Residue Chemistry Branch.
Partial Response (July 15, 1987) by Centre International 
d'Etudes du Lindane (CIEL) to Data Gap S171-4 (Nature of the
Residue in Livestock Poultry) as Identified in the Residue 
Chemistry Chapter of the September 30, 1985 Lindane 
Registration Standard - (RCB No. 3315). MRID No. 402713-01.

March 24, 1988. Memorandum. 4 Page(s).
Nancy Dodd. Residue Chemistry Branch.
ID No. 359-686 (RCB No. 3257). Lindane Registration 
Standard Followup. Analytical Methods for Plants. 
MRID Nos. 404312-02 and 404312-06.

March 24, 1988. Memorandum. 7 Page(s).
Nancy Dodd. Residue Chemistry Branch.
ID No. 359-686 (RCB No. 3260) - Lindane Registration 
Standard Followup, Storage Stability - MRID Nos. 404312-03 
and 404312-06.

March 24, 1988. Memorandum. 4 Page(s).
Nancy Dodd. Residue Chemistry Branch.
ID No. 359-686 (RCB No. 3261) - Lindane Registration 
Standard Followup - Analytical Methods for Animal Tissues, 
Eggs, and Milk - MRID No. 404312-08.

March 24, 1988. Memorandum. 15 Page(s).
Nancy Dodd. Residue Chemistry Branch.
ID No. 359-686 (RCB No. 3259) - Lindane Registration 
Standard Followup - Residues from Seed Treatment - 
MRID No. 404312-07.

March 31, 1988. Memorandum. 3 Page(s).
Cynthia Deyrup. Residue Chemistry Branch.
Goat Metabolism Study Submitted by CIEL in Response to 
Lindane Registration Standard Data Call-In. Deference to 
Tox on the Need for a More Adequate Identification of 
Residues in Goat Liver and Kidney.

April 11, 1988. Review. 5 Page(s).
Michael Firestone. Exposure Assessment Branch.
Protocol Review for Exposure Study.

May 19, 1988. Memorandum. 2 Page(s).
John Doherty. Toxicology Branch.
Lindane: Toxicology Branch Response to Residue Chemistry 
Branch Inquiry Concerning More Adequate Identification of 
Lindane Residues in Goat Liver and Kidney.

June 16, 1988. Memorandum. 23 Page(s).
John Doherty. Toxicology Branch.
Lindane: Meeting with the CIEL Group to Discuss the Current
Status of Toxicity Testing and the Revised Protocol for the 
Rabbit 90-Day Subchronic Dermal Toxicity Study. 
Pages 5-23 removed, registrant data.

July 5, 1988. Review. 2 Page(s).
Paul Mastradone. Exposure Assessment Branch.
3 Progress Reports for 2 Forestry Dissip. Studies 
(GA and MT).

July 5, 1988. Review. 8 Page(s).
Paul Mastradone. Exposure Assessment Branch.
Review Waiver Request for Terrestrial Part of 
Forestry Dissip.

July 11, 1988. Memorandum. 3 Page(s).
John Doherty. Toxicology Branch.
Lindane: Toxicology Branch Response to a Letter from the 
Law Firm of McKenna, Conner and Cuneo Regarding the Summary 
of a Meeting Held on June 9, 1988 in which the Potential for
Lindane to Induce Kidney Lesions and the Protocol for a 
Subchronic Dermal Toxicity Study with Lindane were Discussed.

August 23, 1988. Memorandum. 4 Page(s).
Stephanie Willett. Dietary Exposure Branch.
ID No. 52904-C. Lindane Registration Standard Followup. 
Storage Stability Data. MRID No. 406605-02. RCB No. 4035.

August 24, 1988. Memorandum. 12 Page(s).
Gary Otakie. Residue Chemistry Branch.
Partial Response (June 9, 1988) by Centre International 
d'Etudes du Lindane (CIEL) to Data Gap Section 171-4 
(Magnitude of the Residue in Poultry and Eggs) as Identified
in the Residue Chemistry Chapter of the September 30, 1985 
Lindane Registration Standard - (RCB No. 4034)..

August 29, 1988. Memorandum. 5 Page(s).
Stephanie Willett. Dietary Exposure Branch.
ID No. 52904-C. Lindane Registration Standard Followup. 
Residues in Swine. MRID No. 406605-04. DEB No. 4038.

August 31, 1988. Memorandum. 16 Page(s).
Martin Kovacs. Dietary Exposure Branch.
Partial Response (April 7, 1988) by Centre International 
d'Etudes du Lindane (CIEL) to Data GAP Section 171-4 
[Magnitude of Residue in Animals (Sheep)] as Identified in 
the Residue Chemistry Chapter of the September 30, 1985 
Lindane Registration Standard - (DEB No. 4036)..

September 19, 1988. Review. 21 Page(s).
Paul Mastradone. Environmental Fate & Groundwater Branch.
Review Three Leaching Studies.

September 20, 1988. Memorandum. 22 Page(s).
Martin Kovacs. Dietary Exposure Branch.
Partial Response (December 15, 1987) by Centre International
d'Etudes du Lindane (CIEL) to Data Gap 171-4 [Magnitude of 
Residue in Animals (Dairy Cattle Meat and Milk)] as 
Identified in the Residue Chemistry Chapter of the Sept. 30,
1985 Lindane Registration Standard (RCB No. 4037)..

September 30, 1988. Memorandum. 8 Page(s).
John Doherty. Toxicology Branch.
EPA ID No. 52904-C - Lindane - Review of a Subchronic 
(Scheduled for 13 Weeks) Dermal Toxicity Study which was 
Terminated After 12 Days Because of High Mortality.

October 24, 1988. Report. 9 Page(s).
CDFA Medical Toxicology Branch.
Summary of Toxicology Data - Lindane.

January 23, 1989. Memorandum. 6 Page(s).
John Doherty. Toxicology Branch.
California Department of Food and Agriculture - 
EPA Toxicology Review for Lindane.

February 21, 1989. Memorandum. 3 Page(s).
Linda Propst. Dietary Exposure Branch.
52251-6. OR-CAL Colloidal Lindane. Tolerance or Label 
Restriction Against Using on Turf Grass Grown for Seed. 
No MRID Number. DEB No. 4867.

February 27, 1989. Memorandum. 4 Page(s).
Susan Hummel. Dietary Exposure Branch.
Maneb, Thiabendazole, and Lindane. EPA Reg. Nos.: 
8203-38 Granox Plus Flowable Cereal Seed Treatment Fungicide
8203-39 Granox Plus Cereal Seed Treatment Fungicide 
8203-36 Granol Plus Flowable Insecticide and Fungicide 
Cereal Seed Treatment..

March 15, 1989. Review. 12 Page(s).
Richard Felthousen. Ecological Effects Branch.
Submission of R-Winged Blackbird 14-Day Dietary Toxicity 
Study in Response to Registration Standard.

May 18, 1989. Memorandum. 20 Page(s).
John Doherty. Toxicology Branch.
EPA Id. No. 52904-C. Lindane: Review of a 13-Week Dermal 
Toxicity Study with Rats. 
Tox review 007189.

August 21, 1989. Review. 5 Page(s).
Paul Mastradone. Environmental Fate & Groundwater Branch.
Review Data Submitted in Response to Registration Standard.

August 21, 1989. Data Eval. Rec. 3 Page(s).
Richard Mahler. Environmental Fate & Groundwater Branch.
Metabolism of lindane in soil under aerobic 
and anaerobic conditions. 
MRID No. 406225-01 (1/2).

August 21, 1989. Data Eval. Rec. 3 Page(s).
Richard J. Mahler. Environmental Fate & Groundwater Branch.
Metabolism of lindane in soil under aerobic 
and anaerobic conditions. 
MRID No. 406225-01 (2/2).

August 21, 1989. Data Eval. Rec. 23 Page(s).
Richard Mahler. Environmental Fate & Groundwater Branch.
Field dissipation study on lindane for 
terrestrial uses on peaches in Donalsonville, Georgia. 
MRID No. 406225-02.

August 21, 1989. Data Eval. Rec. 3 Page(s).
Richard Mahler. Environmental Fate & Groundwater Branch.
Field dissipation study on lindane for 
terrestrial uses on tomatoes, Porterville, California. 
MRID No. 406225-03.

August 21, 1989. Data Eval. Rec. 7 Page(s).
Richard Mahler. Environmental Fate & Groundwater Branch.
The volatilization of lindane from soil. 
MRID No. 406225-04.

August 25, 1989. Review. 6 Page(s).
Richard Felthousen, et. al. Ecological Effects Branch.
Submission of Bobwhite Quail 14-Day Dietary Toxicity 
Study in Response to Registration Standard.

August 30, 1989. Memorandum. 20 Page(s).
John Doherty. Toxicology Branch.
EPA Id# 52904-C. Lindane: Review of interim 
report of the rat chronic feeding/oncogenicity 
study with lindane (Life Sciences Research, 
#88/CIL002/816, 3/7/89) covering the 30 day and 26 
week interim sacrifices. Confirmation that male (continued).
Attachment(s) following:

     August 30, 1989. Memorandum. Page(s).
     John Doherty. Toxicology Branch.
     rat kidney is a target organ for lindane toxicity. 
     Request for quantitative data on alpha 2u 
     globulins in male kidney tissue. 
     MRID 410914-01 
     Tox review 007461.

March 20, 1990. Memorandum. 5 Page(s).
James Akerman. Ecological Effects Branch.
Aquatic Invertebrate Life-cycle Study for Daphnia magna 
(Accession No. 400561-06) for Lindane Technical.

March 20, 1990. Memorandum. 7 Page(s).
James Akerman. Ecological Effects Branch.
Early Life Stage Study for Rainbow Trout Salmo gairdneri 
(Accession No. #400561-05) for Lindane Technical.

April 10, 1990. Memorandum. 14 Page(s).
Marion Copley. Toxicology Branch.
ID 009001-9. Lindane: Evaluate Immunohistochemical 
Report for Localization of Alpha 2u Globulin in Kidneys 
in Rats 
Pages 4-14 removed, registrant data. 
Tox review 007859.

January 31, 1991. Memorandum. 109 Page(s).
E. Zager. Chemistry Branch II.
Lindane Product and Residue Chemistry Reregistration 
Standard Updates and CBRS # 6961. 
Pages 11-12 removed, quality control information. Pages 
25-40 removed, quality control, manufacturing process 
and impurity information.

March 18, 1991. Memorandum. 1 Page(s).
John Doherty. Toxicology Branch.
Special Neurotoxicity Testing for Lindane.

July 9, 1991. Memorandum. 3 Page(s).
George Tompkins. Environmental Fate & Groundwater Branch.
Environmental Fate Studies to be Included in Data Call-In 
Notice for Lindane (009001).

August 14, 1991. Memorandum. 3 Page(s).
Doug Urban. Ecological Effects Branch.
Lindane: List A Project. Report of Data and 
Study Requirements.

September 27, 1991. Memorandum. 21 Page(s).
John Doherty. Toxicology Branch.
EPA Id. # (No Number Provided): "Technical" Lindane: 
Review of a 13-Week Dermal Toxicity Study with Rabbits 
Including a 6-Week Recovery Phase. Study Includes Special 
Assessment of the Kidney and Bone Marrow Myelograms. 
Tox Review 008610.

September 1, 1994. Review. 5 Page(s).
Alfred Smith. Reregistration Support Branch.
Product Chemistry Review of Drexel Lindane Technical 
Page 5 deleted - Confidential Statement of Formula.


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